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Ethinyl estradiol and norethindrone HRT
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Ethinyl estradiol and norethindrone (HRT)

Generic name: ethinyl estradiol and norethindrone (HRT) [ ETH-in-ill-ESS-tra-DYE-ole-and-nor-ETH-in-drone ]
Brand names: femhrt 0.5 mg/2.5 mcg, Fyavolv, Jevantique Lo, Jinteli
Dosage form: oral tablet (2.5 mcg-0.5 mg; 5 mcg-1 mg)
Drug classes:Contraceptives, Sex hormone combinations

Medically reviewed by Drugs.com on Sep 6, 2021. Written by Cerner Multum.

What is ethinyl estradiol and norethindrone?

Ethinyl estradiol is a form of estrogen. Estrogen is a female sex hormone necessary for many processes in the body.

Norethindrone is a form of progesterone. Progesterone is a female hormone important for the regulation of ovulation and menstruation.

Ethinyl estradiol and norethindrone HRT (hormone replacement therapy) is a combination medicine used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. It is also used to prevent osteoporosis.

Ethinyl estradiol and norethindrone may also be used for purposes not listed in this medication guide.

Warnings

You should not use ethinyl estradiol and norethindrone if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, if you will have major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.

Do not use if you are pregnant.

This medicine may increase your risk of developing a condition that may lead to uterine cancer. Report any unusual vaginal bleeding right away.

Using this medicine can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, or ovaries. Ethinyl estradiol and norethindrone should not be used to prevent heart disease, stroke, or dementia.

Before taking this medicine

You should not use this medicine if you are allergic to ethinyl estradiol or norethindrone, or if you have:

  • unusual vaginal bleeding that has not been checked by a doctor;

  • liver disease;

  • a bleeding disorder;

  • a history of heart attack, stroke, or blood clot; or

  • a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina.

Do not use if you are pregnant. Tell your doctor right away if you become pregnant during treatm...