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Etidronate Oral, Intravenous
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Etidronate

Medically reviewed by Drugs.com. Last updated on Feb 13, 2022.

Commonly used brand name(s)

In the U.S.

  • Didronel

Available Dosage Forms:

  • Tablet

Therapeutic Class: Calcium Regulator

Chemical Class: Bisphosphonate

Uses for etidronate

Etidronate is used to treat Paget's disease of the bone. It may also be used to treat or prevent a certain type of bone problem (heterotopic ossification) after hip replacement surgery or spinal injury.

Etidronate is also used to treat hypercalcemia (too much calcium in the blood) that may occur with some types of cancer.

Etidronate is available only with your doctor's prescription.

Before using etidronate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For etidronate, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to etidronate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of etidronate in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of etidronate in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving etidronate.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other medical problems

The presence of other medical problems may affect the use of etidronate. Make sure you tell your doctor if you have any other medical problems, especially:

  • Anemia or
  • Blood clotting problems or
  • Cancer or
  • Dental or tooth problems or
  • Dental procedures (eg, tooth extraction) or
  • Infection or
  • Poor oral hygiene or
  • Surgery (eg, dental surgery)—May increase risk for severe jaw problems. This risk may also be increased if you use etidronate for ...