Factor xiii (Intravenous)

Medically reviewed by Drugs.com. Last updated on May 11, 2022.

Commonly used brand name(s)

In the U.S.

Corifact
Tretten

Available Dosage Forms:

Powder for Solution

Therapeutic Class: Hemostatic

Uses for factor xiii

Factor XIII injection is used to prevent bleeding in patients with congenital Factor XIII deficiency.

Factor XIII is a protein that is produced naturally in the body. Corifact™ or Tretten® is a man-made protein produced to replicate the naturally occurring factor XIII in the body. It is used to stop bleeding by helping the blood to clot.

Factor xiii is to be given only by or under the supervision of your doctor or other health care professional.

Before using factor xiii

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For factor xiii, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to factor xiii or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Factor XIII injection in children.

Geriatric

Appropriate studies have not been performed on the relationship of age to the effects of Factor XIII injection in the geriatric population. Safety and efficacy have not been established.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving factor xiii, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using factor xiii with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Coagulation Factor VIIa

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Factor xiii Intravenous