Fam-trastuzumab deruxtecan
Generic name: fam-trastuzumab deruxtecan [ FAM-tras-TOOZ-ue-mab-DER-ux-TEE-kan ]
Brand name: Enhertu
Dosage form: intravenous powder for injection (100 mg)
Drug class:HER2 inhibitors
What is fam-trastuzumab deruxtecan?
Fam-trastuzumab deruxtecan is used to treat HER2-positive breast cancer that has spread to other parts of the body (metastatic) or cannot be removed with surgery.
Fam-trastuzumab deruxtecan is also used to treat a certain type of HER2-positive esophageal cancer.
Fam-trastuzumab deruxtecan is usually given after other cancer treatments did not work or have stopped working.
Fam-trastuzumab deruxtecan may also be used for purposes not listed in this medication guide.
Warnings
Fam-trastuzumab deruxtecan can cause serious or life-threatening side effects on your heart or lungs. Call your doctor right away if you have a cough, tiredness, dizziness, chest tightness, wheezing, irregular heartbeats, new or worsening shortness of breath.
Fam-trastuzumab deruxtecan can weaken (suppress) your immune system, and you may get an infection or bleed more easily. Tell your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, weakness, cold or flu symptoms, frequent or recurring illness).
Both men and women using fam-trastuzumab deruxtecan should use effective birth control to prevent pregnancy.Birth control should be continued for 7 months after the last dose of fam-trastuzumab deruxtecan in women and 4 months after in men.
Before taking this medicine
Tell your doctor if you have ever had:
heart problems;
breathing problems; or
an infection.
You may need to have a negative pregnancy test before starting this treatment.
Fam-trastuzumab deruxtecan can harm an unborn baby if the mother or the father is using this medicine.
If you are a woman, do not use fam-trastuzumab deruxtecan if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 7 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using fam-trastuzumab deruxtecan.
This medicine may affect fertility (ability to have children), in men.
Do not breastfeed while using this medicine, and for at least 7 months after your last d...
