#
Famotidine and ibuprofen
  • Drugs A to Z

Famotidine and ibuprofen

Generic name: famotidine and ibuprofen [ fam-OH-ti-deen-and-EYE-bue-PROE-fen ]
Brand name: Duexis
Dosage form: oral tablet (26.6 mg-800 mg)
Drug class:Nonsteroidal anti-inflammatory drugs

Medically reviewed by Drugs.com on Nov 3, 2020. Written by Cerner Multum.

What is famotidine and ibuprofen?

Famotidine decreases the amount of acid the stomach produces.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain.

Famotidine and ibuprofen is a combination drug. Ibuprofen treats the symptoms of arthritis. Famotidine helps reduce the risk of ulcers in the stomach or intestines that can be caused by long-term use of ibuprofen.

Taking famotidine (Pepcid) and ibuprofen (Advil, Motrin) together does not have the same effect as using the combination medicine.

Famotidine and ibuprofen may also be used for purposes not listed in this medication guide.

Warnings

Ibuprofen can increase your risk of fatal heart attack or stroke. Do not use famotidine and ibuprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal.

Before taking this medicine

You should not use this medicine if you are allergic to famotidine or ibuprofen, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Ibuprofen can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using famotidine and ibuprofen, especially in older adults.

Tell your doctor if you have ever had:

  • heart disease, high blood pressure;

  • bleeding problems;

  • liver or kidney disease;

  • a stomach or intestinal disorder;

  • a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, or lupus;

  • asthma; or

  • if you smoke or drink alcohol.

If you are pregnant, you should not take ibuprofen unless your doctor tells you to. Taking an NSAID d...