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Felimazole
  • Professionals
  • FDA PI

Felimazole

Generic name: methimazole
Dosage form: tablet, sugar coated
Drug class:Antithyroid agents

Medically reviewed by Drugs.com. Last updated on Apr 21, 2022.

For oral use in cats only.

CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.

DESCRIPTION: Methimazole is a thioureylene antithyroid drug, which inhibits the synthesis of thyroid hormones. Methimazole (1-methylimidazole-2-thiol) is a white, crystalline substance that is freely soluble in water. The chemical formula is C4H6N2S. Molecular weight is 114.16.

Methimazole Chemical Structure

INDICATION: Felimazole Coated Tablets (methimazole) are indicated for the treatment of hyperthyroidism in cats.

DOSAGE AND ADMINISTRATION: The starting dose of Felimazole Coated Tablets is 2.5 mg administered every 12 hours. Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. Dose adjustments should be made in 2.5 mg increments. The maximum total dosage is 20 mg per day divided, not to exceed 10 mg as a single administration.

Hematology, biochemistry, and TT4 should be evaluated prior to initiating treatment and monitored after 3 weeks and 6 weeks of treatment. There...