Generic name:fludrocortisone acetate
Dosage form: Tablets
Drug class:Mineralocorticoids
Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.
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Description
Florinef Acetate (Fludrocortisone Acetate Tablets USP) contains fludrocortisone acetate, a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity; it is used only for its mineralocorticoid effects. The chemical name for fludrocortisone acetate is 9-fluoro- 11ß,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate; its graphic formula is:
Florinef Acetate is available for oral administration as scored tablets providing 0.1 mg fludrocortisone acetate per tablet. Inactive ingredients: calcium phosphate, corn starch, lactose, magnesium stearate, sodium benzoate, and talc.
Clinical Pharmacology
Corticosteroids are thought to act, at least in part, by controlling the rate of synthesis of proteins. Although there are a number of instances in which the synthesis of specific proteins is known to be induced by corticosteroids, the links between the initial actions of the hormones and the final metabolic effects have not been completely elucidat...
