Flurbiprofen (EENT)

Class: Nonsteroidal Anti-inflammatory Agents
- Nonsteroidal Anti-inflammatory Agents, Ophthalmic
- NSAIAs, EENT
- NSAIDs, EENT
ATC Class: S01BC04
VA Class: OP900
Molecular Formula: C₁₅H₁₃FO₂•Na
CAS Number: 56767-76-1
Brands: Ocufen

Medically reviewed by Drugs.com on Jul 22, 2021. Written by ASHP.

Introduction

Prototypical NSAIA; propionic acid derivative.

Uses for Flurbiprofen (EENT)

Inhibition of Intraoperative Miosis

Prophylactically before ocular surgery (e.g., cataract extraction) to prevent or reduce intraoperative miosis.

Postoperative Ocular Inflammation

Has been used for prevention and management of postoperative ocular inflammation† associated with argon laser trabeculoplasty and cyclocryotherapy.

Cystoid Macular Edema

Has been used for prevention of postoperative cystoid macular edema† associated with cataract extraction.

Inhibition of Corneal Neovascularization

Has been reported to inhibit corneal neovascularization† induced by chemical or thermal burns or prolonged use of contact lenses in preliminary research in animals.

Flurbiprofen (EENT) Dosage and Administration

Administration

Ophthalmic Administration

Apply topically to the eye as an ophthalmic solution.

Avoid contamination of the solution container.

Dosage

Available as flurbiprofen sodium; dosage expressed in terms of flurbiprofen sodium.

Adults

Inhibition of Intraoperative Miosis

Ophthalmic

1 drop of 0.03% solution into the eye(s) undergoing surgery beginning 2 hours before the surgery; repeat at approximately 30-minute intervals for a total of 4 drops per affected eye.