Generic name: Fluticasone propionate
Dosage form: cream
Drug class:Topical steroids
Medically reviewed by Drugs.com. Last updated on Apr 1, 2022.
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Fluticasone Description
Fluticasone Propionate Cream, USP 0.05% contains Fluticasone propionate [(6α,11β,16α,17α)-6,9,-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid, S-fluoromethyl ester], a synthetic fluorinated corticosteroid, for topical dermatologic use. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents.
Chemically, Fluticasone propionate is C 25H 31F 3O 5S. It has the following structural formula:
Fluticasone propionate has a molecular weight of 500.6. It is a white to off-white powder and is insoluble in water.
Each gram of Fluticasone Propionate Cream, USP 0.05% contains Fluticasone propionate 0.5 mg in a base of propylene glycol, mineral oil, cetostearyl alcohol, Ceteth-20, isopropyl myristate, dibasic sodium phosphate, citric acid, purified water, and methylparaben as preservative.
CLINICAL PHARMACOLOGY
Like other topical corticosteroids, Fluti...
