Fluticasone (EENT)

Class: Corticosteroids
VA Class: NT200
Molecular Formula: C₂₅H₃₁F₃O₅S
CAS Number: 80474-14-2
Brands: Flonase

Medically reviewed by Drugs.com on Jul 22, 2021. Written by ASHP.

Introduction

Synthetic trifluorinated corticosteroid.

Uses for Fluticasone (EENT)

Seasonal and Perennial Rhinitis

Symptomatic treatment of seasonal or perennial rhinitis when conventional therapy with antihistamines or decongestants is ineffective or is not tolerated.

Generally provides symptomatic relief of watery rhinorrhea, nasal congestion, sneezing, postnasal drip, and nasal itching; generally does not relieve signs and symptoms of conjunctivitis, although improvement in ophthalmic manifestations may occur.

Relieves symptoms in both allergic and nonallergic rhinitis, although experience is more extensive with allergic rhinitis.

Has been used successfully prior to the onset of the pollen season for the prophylaxis of symptoms of seasonal allergic rhinitis†.

Fluticasone (EENT) Dosage and Administration

Administration

Intranasal Administration

Administer by nasal inhalation using a metered-dose nasal spray pump.

Avoid contact with the eyes.

If used once daily, administer preferably in the morning. Generally, initiate therapy with once-daily dosing; some patients may obtain greater relief with twice-daily divided dosing.

Although regular dosing generally provides optimal benefit, as needed (prn) dosing may be adequate in some patients with seasonal allergic rhinitis.

Clear nasal passages prior to administration. If nasal passages are blocked, a topical nasal decongestant can be administered 5–15 minutes before intranasal administration.

Prime pump prior to initial use or after a period of nonuse (i.e., ≥1 week).

Tilt the head slightly forward, insert the nasal ada...