Folotyn
Generic name:pralatrexate [ PRAL-a-TREX-ate ]
Drug class:Antimetabolites
What is Folotyn?
Folotyn is a cancer medication.
Folotyn is used to treat T-cell lymphoma that has spread throughout the body.
Folotyn is given for relapsed T-cell lymphoma, or after other medications have been tried without successful treatment.
Warnings
Before you receive Folotyn, tell your doctor if you have kidney disease.
Folotyn can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
Do not use pralatrexate if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. You should not breast-feed a baby while you are being treated with Folotyn. You may be required to take oral folic acid supplements and receive vitamin B12 injections to help prevent some of the side effects of Folotyn. Follow your doctor's medication instructions very closely.
Before taking this medicine
Tell your doctor if you have ever had liver or kidney problems.
You may need to have a negative pregnancy test before starting treatment with Folotyn.
Pralatrexate can harm an unborn baby if the mother or the father is using this medicine.
If you are a woman, do not use Folotyn if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Folotyn.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
How is Folotyn given?
Folotyn is given as an infusion into a vein. A healthcare provider will give you this injection.
Folotyn is usually given once per week for up to 6 weeks at a time.
Your doctor may have you take folic acid supplements before, during, and after your treatment with Folotyn. You may also receive vitamin B12 injections every 8 to 10 weeks. This can help protect your blood cells from certain side effects of pralatrexate.
Follow your doctor's dosing instructions very carefully.
Folotyn can increase your risk of bleeding or infection. You will need frequent medical tests. Your cancer treatments may be delayed based on the results.
Dosing information
Usual Adult Dose for Lymph...
