Medically reviewed by Drugs.com. Last updated on May 30, 2022.
Epidural or spinal hematomas, which may result in long-term or permanent paralysis, can occur in patients who are anticoagulated with low molecular weight heparins, heparinoids, or fondaparinux sodium and are receiving neuraxial anesthesia or undergoing spinal puncture. Use of indwelling epidural catheters, concomitant use of drugs affecting hemostasis (eg, NSAIDs, platelet inhibitors, or other anticoagulants), history of traumatic or repeated epidural or spinal puncture, spinal deformity, or spinal surgery may increase the risk of developing these hematomas. Monitor patients frequently for neurological impairment. If neurological compromise is noted, urgent treatment is necessary .
Commonly used brand name(s)
In the U.S.
- Arixtra
Available Dosage Forms:
- Solution
Therapeutic Class: Anticoagulant
Pharmacologic Class: Factor Xa Inhibitor
Uses for fondaparinux
Fondaparinux is used to prevent deep vein thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism. Fondaparinux is used for several days after hip fracture surgery, hip or knee replacement surgery, and in some cases following abdominal or stomach surgery, while you are unable to walk. It is during this time that blood clots are most likely to form.
Fondaparinux is also used together with warfarin to treat acute deep vein thrombosis (blood clot in the leg) and pulmonary embolism (blood clot in the lung).
Fondaparinux is available only with your doctor's prescription.
Before using fondaparinux
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fondaparinux, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to fondaparinux or any other medicines. Also tell your health care professional if you have any other types of allergies, s..
