Fosnetupitant and palonosetron (injection)
Generic name: fosnetupitant and palonosetron (injection) [ FOS-net-UE-pi-tant-and-PAL-oh-NOE-se-tron ]
Brand names: Akynzeo for Injection, Akynzeo Injection
Dosage form: intravenous powder for injection (235 mg-0.25 mg)
Drug class:Miscellaneous antiemetics
What is fosnetupitant and palonosetron?
Fosnetupitant and palonosetron is a combination medicine used to help prevent nausea and vomiting caused by chemotherapy. fosnetupitant and palonosetron is given together with a steroid called dexamethasone.
Fosnetupitant and palonosetron helps prevent nausea and vomiting that occurs both during chemotherapy and later on (delayed nausea and vomiting).
Fosnetupitant and palonosetron may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Fosnetupitant and palonosetron may harm an unborn baby. Tell your doctor if you become pregnant.
Tell your doctor if you have ever had:
liver or kidney disease; or
an allergic reaction to a medicine for nausea or vomiting, such as dolasetron (Anzemet), ondansetron (Zofran), or palonosetron (Aloxi).
Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, or serious infections. These medicines may interact with fosnetupitant and palonosetron and cause a serious condition called serotonin syndrome.
You should not breast-feed while using fosnetupitant and palonosetron.
Fosnetupitant and palonosetron is not approved for use by anyone younger than 18 years old.
How is fosnetupitant and palonosetron given?
This medicine is given ahead of time and will not treat nausea or vomiting you already have.
About 30 minutes before chemotherapy, a healthca...
