Fostamatinib
Generic name: fostamatinib [ FOS-ta-MA-ti-nib ]
Brand name: Tavalisse
Dosage form: oral tablet (100 mg; 150 mg)
Drug class:Miscellaneous coagulation modifiers
What is fostamatinib?
Fostamatinib is used to treat chronic immune thrombocytopenia, a bleeding condition caused by a lack of platelets in the blood. fostamatinib is given after other treatments have failed.
Fostamatinib may also be used for purposes not listed in this medication guide.
Warnings
Fostamatinib can raise your blood pressure, sometimes to dangerous levels. Fostamatinib may also cause liver problems, severe diarrhea, and infections.
Call your doctor if you have: headaches, chest pain, shortness of breath, severe diarrhea, stomach pain, fever, or sore throat.
Before taking this medicine
Fostamatinib is not approved for use by anyone younger than 18 years old.
Tell your doctor if you have ever had:
liver problems.
Do not use fostamatinib if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using fostamatinib and for at least 1 month after your last dose.
Do not breast-feed while using this medicine, and for at least 1 month after your last dose.
How should I take fostamatinib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take fostamatinib with or without food.
Fostamatinib can cause diarrhea. You may need to change your diet, drink extra fluids, or take anti-diarrhea medication. Follow your doctor's instructions for treating or preventing diarrhea.
Fostamatinib can raise your blood pressure, sometimes to dangerous levels. Your blood pressure will need to be checked often.
You will also need frequent medical tests. Your doctor may change your dose, or you may need to stop using fostamatinib based on test results.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
