Fostamatinib disodium (Oral)

Medically reviewed by Drugs.com. Last updated on May 7, 2022.

Pharmacologic Class: Fostamatinib

Uses for fostamatinib disodium

Fostamatinib is used to treat low platelet levels (thrombocytopenia) in the blood in patients with chronic immune thrombocytopenia (ITP) who have received treatment that did not work well.

Fostamatinib disodium is available only with your doctor's prescription.

Before using fostamatinib disodium

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fostamatinib disodium, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to fostamatinib disodium or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies on the relationship of age to the effects of fostamatinib have not been performed in the pediatric population. Use is not recommended in children. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fostamatinib in the elderly. However, elderly patients are more likely to have serious unwanted effects, which may require caution in patients receiving fostamatinib.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving fostamatinib disodium, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using fostamatinib disodium with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Abametapir
Carbamazepine
Enzalutamide
Fedratinib
Fexinidazole
Fosphenytoin
Lumacaftor
Mitotane
Phenytoin
Rifampin
St John's Wort
Voriconazole

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Fostamatinib disodium