Gadoversetamide (Intravenous)
Medically reviewed by Drugs.com. Last updated on Mar 26, 2022.
Patients with impaired renal function receiving gadolinium-based contrast agents have an increased risk of nephrogenic systemic fibrosis, which may result in fatal or debilitating fibrosis of the internal organs, skin, or muscles. Avoid use in this population unless required diagnostic information is not attainable with noncontrasted imaging. Screen patients for conditions that may affect renal function prior to administration and measure GFR if present. Do not use in patients with chronic (GFR less than 30 mL/min) or acute kidney injury, do not exceed the recommended dose, and allow time for the contrast to be removed from the body before readministration .
Uses for gadoversetamide
Gadoversetamide injection is used to help diagnose or find problems in the brain, spine, head, neck, liver, and other parts of your body. It is a gadolinium-based contrast agent (GBCA) used in magnetic resonance imaging (MRI) scans. Contrast agents are used to help create a clear picture of the different parts of the body during certain medical procedures, such as MRI scans. MRI scans use magnets and computers to create images or “pictures” of certain areas inside the body. Unlike x-rays, they do not involve ionizing radiation.
Gadoversetamide is to be given only by or under the direct supervision of your doctor.
Before using gadoversetamide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For gadoversetamide, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to gadoversetamide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of gadoversetamide injection in the pediatric population. However, pediatric patients with serious kidney problems may require caution in patients receiving gadoversetamide. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of gadoversetamide injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution in patients receiving gadoversetamide.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
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