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Gamifant
  • Treatments
  • Hemophagocytic Lymphohistiocytosis

Gamifant

Generic name:emapalumabEM-a-PAL-ue-mab ]
Drug class:Selective immunosuppressants

Medically reviewed by Drugs.com on Jul 20, 2021. Written by Cerner Multum.

What is Gamifant?

Gamifant is used together with a medicine called dexamethasone to treat hemophagocytic lymphohistiocytosis (HLH), a rare disease that is sometimes inherited. HLH causes your immune system to attack healthy blood cells, which can lead to serious or life-threatening side effects on your spleen or liver. This medicine is for use in adults and children as young as newborn.

Gamifant is given after other treatments did not work or have stopped working.

Gamifant may also be used for purposes not listed in this medication guide.

Warnings

Gamifant affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, night sweats, skin sores, cough, trouble breathing, or cough with bloody mucus.

Before taking this medicine

Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.

Tell your doctor if you have ever had:

  • a positive tuberculosis (TB) skin test;

  • any type of infection (active or recent);

  • histoplasmosis (a fungal infection);

    ...