Garamycin Eye Drops
Generic name:gentamicin sulfate
Dosage form: ophthalmic solution
Drug class:Ophthalmic anti-infectives
Medically reviewed by Drugs.com. Last updated on Jun 21, 2021.
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The Garamycin Ophthalmic brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
DESCRIPTION:
Gentamicin Sulfate is a water soluble antibiotic of the aminoglycoside group. Gentamicin Sulfate Ophthalmic Solution is a sterile, aqueous solution buffered with dibasic sodium phosphate and monobasic sodium phosphate to approximately pH 7 (pH range 6.5 - 7.5) for ophthalmic use. Each mL contains gentamicin sulfate, USP (equivalent to 3 mg gentamicin base), sodium chloride and benzalkonium chloride (0.1 mg) as a preservative.
Gentamicin is obtained from cultures of Micromonosporapurpurea. It is a mixture of the sulfate salts of gentamicin C1, C2, and C1A. All three components appear to have similar antimicrobial activities. Gentamicin Sulfate occurs as a white powder and is soluble in water and insoluble in alcohol.
The structure is as follows:
CLINICAL PHARMACOLOGY:
Microbiology:
Gentamicin sulfate is active in vitro against many strains of the following microorganisms:
Staphylococcusaureus, Staphylococcusepidermidis,Streptoccuspyogenes, Streptococcus pneumonia,Enterobacteraerogenes, Escherichia coli,Haemophilusinfluenza,
