Garamycin Eye Ointment
Generic name:gentamicin sulfate
Dosage form: ophthalmic ointment
Drug class:Ophthalmic anti-infectives
Medically reviewed by Drugs.com. Last updated on Aug 23, 2021.
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The Garamycin Ophthalmic brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
DESCRIPTION:
Gentamicin sulfate is a water soluble antibiotic of the aminoglycoside group.
Gentamicin Sulfate Ophthalmic Ointment USP is a sterile ointment for topical ophthalmic use. Each gram contains gentamicin sulfate (equivalent to 3 mg gentamicin) in a base of white petrolatum and mineral oil.
Gentamicin is obtained from cultures of Micromonospora purpurea. Gentamicin sulfate is a mixture of the sulfate salts of gentamicin C1, C2 and C1A. All three components appear to have similar antimicrobial activities. Gentamicin sulfate occurs as a white powder and is soluble in water and insoluble in alcohol. The structural formula is as follows:
CLINICAL PHARMACOLOGY:
Microbiology: Gentamicin sulfate is active in vitro against many strains of the following microorganisms:
Staphylococcus aureus, Staphylococcus epidermidis,
Streptococcus pyogenes, Streptococcus pneumoniae,
Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae,
Klebsiella pneumoniae, Neisseria gonorrhoeae,
Pseudomonas aeruginosa, and Serratia marcescens.
INDICATIONS AND USAGE:
GARAMYCIN Ophthalmic Ointment is indicated in the topical treatment of ocular bacterial infections, including conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, blepharoconjunctivitis, acute meibomianitis, and dacryocystitis caused by susceptible strains of the following microorganisms:
Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus pneumoniae, Enterobacter aerogenes, Escherich..
