Gatifloxacin Eye Drops

Dosage form: ophthalmic solution
Drug class:Ophthalmic anti-infectives

Medically reviewed by Drugs.com. Last updated on Apr 1, 2022.

Indications and Usage for Gatifloxacin Eye Drops

Gatifloxacin ophthalmic solution 0.5 % is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms:

• Aerobic gram-positive bacteria:

Staphylococcus aureus

Staphylococcus epidermidis

Streptococcus mitis group *

Streptococcus oralis*

Streptococcus pneumoniae

• Aerobic gram-negative bacteria:

Haemophilus influenzae

*Efficacy for these organisms were studied in fewer than 10 infections.

Gatifloxacin Eye Drops Dosage and Administration

• Day 1: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times.
• Day 2 through Day 7: Instill one drop two to four times daily in the affected eye(s) while awake.

Dosage Forms and Strengths

Ophthalmic solution: 0.5% gatifloxacin (5 mg/mL)

Contraindications

Gatifloxacin ophthalmic solution 0.5 % is contraindicated in patients with a history of hypersensitivity to gatifloxacin, to other quinolones, or to any of the components in this medication [see Warnings and Precautions (5.1)].

Warnings and Precautions

Hypersensitivity

Some patients receiving topical ophthalmic gatifloxacin experienced hypersensitivity reactions including anaphylactic reactions, angioedema (including pharyngeal, laryngeal, or facial edema), dyspnea, urticaria, and itching, even following a single dose. Rare cases of Stevens-Johnson Syndrome were reported in association with topical ophthalmic gatifloxacin use. If an allergic reaction to gatifloxacin oc...