Gel-One (injection)

Generic name: sodium hyaluronate (injection) [ SO-dee-um-HYE-al-yoo-RON-ate ]
Brand names: Durolane, Euflexxa, Gel-One, Gelsyn-3, Hyalgan, Supartz
Drug class:Viscosupplementation agents

Medically reviewed by Drugs.com on Mar 17, 2022. Written by Cerner Multum.

What is Gel-One?

Gel-One is similar to the fluid that surrounds the joints in your body. This fluid acts as a lubricant and shock absorber for the joints.

Gel-One is used to treat knee pain caused by osteoarthritis.

Gel-One is usually given when other arthritis medications have not been effective.

Gel-One may also be used for purposes not listed in this medication guide.

Warnings

You should not receive a Gel-One if you have an infection in your knee or in the skin around your knee.

Before taking this medicine

You should not receive Gel-One if you are allergic to it, or if you have an infection in your knee or in the skin around your knee.

Gel-One is not approved for use by anyone younger than 21 years old.

Tell your doctor if you have ever had:

• blood clots or circulation problems in your legs; or

• an allergy to birds, feathers, or egg products.

It is not known whether Gel-One will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

How is Gel-One given?

Gel-One is injected directly into your knee joint. A healthcare provider will give you this injection.

Gel-One is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully.

To prevent pain and swelling, your doctor may recommend resting your knee or applying ice for a short time after your injection.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Tell your doctor if your symptoms do not improve, or if they get worse.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Gel-One.

What happens if I overdose?

Since this medication is given by a healthcare professional in ...