#
Abacavir and lamivudine
  • Drugs A to Z

Abacavir and lamivudine

Generic name: abacavir and lamivudine [ a-BAK-a-veer-and-la-MIV-yoo-deen ]
Brand name: Epzicom
Dosage form: oral tablet (600 mg-300 mg)
Drug class:Antiviral combinations

Medically reviewed by Drugs.com on Apr 2, 2021. Written by Cerner Multum.

What is abacavir and lamivudine?

Abacavir and lamivudine are antiviral medicines that prevent human immunodeficiency virus (HIV) from multiplying in your body.

Abacavir and lamivudine is a combination medicine used to treat HIV, the virus that can cause the acquired immunodeficiency syndrome (AIDS). This medication is not a cure for HIV or AIDS.

Abacavir and lamivudine may also be used for purposes not listed in this medication guide.

Warnings

You should not take abacavir and lamivudine if you have liver disease, or if you have ever tested positive for a gene variation called HLA-B*5701. Do not take this medicine if you have ever had an allergic reaction to any medicine that contains abacavir or lamivudine.

Stop taking abacavir and lamivudine and call your doctor at once if you have signs of an allergic reaction: fever; rash; nausea, vomiting, diarrhea, stomach pain; general ill feeling, extreme tiredness, body aches; shortness of breath, cough, sore throat.

If you've ever had hepatitis B, it may become active or get worse after you stop using abacavir and lamivudine. You may need frequent liver function tests for several months.

Before taking this medicine

You should not use this medicine if you are allergic to abacavir or lamivudine, or:

  • if you have liver disease;

  • if you have ever tested positive for a gene variation called HLA-B*5701; or

  • if you have ever had an allergic reaction to any medicine that contains abacavir or lamivudine (Combivir, Epivir, Triumeq, Trizivir, Ziagen).

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, if you are overweight, or if you are a woman. Ask your doctor about your risk.

Tell your doctor if you have ever had:

  • liver disease (especially hepatitis B or C);

  • kidney disease;

  • heart problems or risk factors such as diabetes,