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Glucovance
  • Treatments
  • Diabetes
  • Type 2

Glucovance

Generic name:glyburide and metforminGLYE-bure-ide-and-met-FOR-min ]
Drug class:Antidiabetic combinations

Medically reviewed by Jane Grigg, DipPharm. Last updated on Apr 21, 2022.

What is Glucovance?

Glucovance contains a combination of glyburide and metformin. Glyburide and metformin are both oral diabetes medicines that help control blood sugar levels.

Glucovance is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Glucovance is not for treating type 1 diabetes.

Warnings

You should not use Glucovance if you have severe kidney disease, if you also take bosentan (Tracleer), or if you have metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Glucovance.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

Before taking this medicine

You should not use Glucovance if you are allergic to glyburide or metformin, or:

  • severe kidney disease;

  • metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment); or

  • if you are also using bosentan (to treat

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