Glycine
Dosage form: irrigation
Drug class:Sterile irrigating solutions
Medically reviewed by Drugs.com. Last updated on May 23, 2022.
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NONELECTROLYTE IRRIGATING FLUID FOR TRANSURETHRAL SURGICAL PROCEDURES.
For Urologic Irrigation Only; Not For Injection By Usual Parenteral Routes
Flexible Irrigation Container
Rx only
Glycine Description
1.5% Glycine Irrigation, USP is a sterile, nonpyrogenic, hypotonic, aqueous solution of Glycine intended only for urologic irrigation during transurethral surgical procedures.
Each 100 mL contains 1.5 g of Glycine in water for injection. The solution is nonelectrolytic, hypotonic and has an osmolarity of 200 mOsmol/liter (calc.); pH 6.0 (4.5 to 6.5).
The solution contains no bacteriostat, antimicrobial agent or added buffer and is intended only for use as a single-dose irrigation. When smaller volumes are required, the unused portion should be discarded.
1.5% Glycine Irrigation is a urologic nonelectrolyte irrigant.
Glycine, USP is chemically designated aminoacetic acid (C2H5NO2), a white crystalline powder freely soluble in water. It has the following structural formula:
NH2CH2COOH
Water for Injection, USP is chemically designated H20.
The flexible plastic container is fabricated from a specially formulated polyvinylchloride. Water can permeate from inside the container into the overwrap but not in amounts sufficient to affect the solution significantly.
The semi-rigid container is fabricated from a specially formulated polyolefin. It is a copolymer of ethylene and propylene. The container requires no vapor barrier to maintain the proper drug concentration.
The flexible plastic container is fabricated from a specially formulated polyvinylchloride. Water can permeate from inside the container into the overwrap but not in amounts sufficient to affect the solution significantly. Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the plastic container materials. Exposure to temperatures above 25°C/77°F during transport a...
