Glycopyrronium

Class: Skin and Mucous Membrane Agents, Miscellaneous
Chemical Name: [(3R)-1,1-dimethylpyrrolidin-1-ium-3-yl] (2S)-2-cyclopentyl-2-hydroxy-2-phenylacetate;[(3S)-1,1-dimethylpyrrolidin-1-ium-3-yl] (2R)-2-cyclopentyl-2-hydroxy-2-phenylacetate
Molecular Formula: C₁₉H₂₈NO₃ • C₇H₇O₃S • H₂O
CAS Number: 1624259-25-1
Brands: Qbrexza

Medically reviewed by Drugs.com on Aug 17, 2021. Written by ASHP.

Introduction

Glycopyrronium tosylate is a skin or mucous membrane agent.

Uses for Glycopyrronium

Glycopyrronium tosylate has the following uses:

Glycopyrronium tosylate is an anticholinergic indicated for topical treatment of primary axillary hyperhidrosis in adults and pediatric patients 9 years of age and older.

Glycopyrronium Dosage and Administration

General

Glycopyrronium tosylate is available in the following dosage form(s) and strength(s):

Cloth: Single-use cloth pre-moistened with 2.4% glycopyrronium solution.

Dosage

It isessentialthat the manufacturer's labeling be consulted for more detailed information on dosage and administration of this drug. Dosage summary:

Glycopyrronium tosylate is for topical use in the underarm area only and not for use in other body areas.
Wash hands immediately with soap and water after applying and discarding the glycopyrronium tosylate cloth. Glycopyrronium tosylate may cause temporary dilation of the pupils and blurred vision if it comes in contact with the eyes. Avoid transfer of glycopyrronium tosylate to the periocular area.
Do not apply glycopyrronium tosylate to broken skin. Avoid using glycopyrronium tosylate with occlusive dressings.

Pediatric Patients

Children 9 years of age and older: Glycopyrronium tosylate should be applied to clean dry skin on the underarm areas once daily. Glycopyrronium tosylate should not be used more frequently than once every 24 hours.

Tear open the pouch and pull out the cloth, unfold the cloth, and wipe it across one entire underarm once. Using the same cloth, wipe the other underarm once. A single cloth should be used to apply glycopyrronium tosylate to both underarms.

Adults

Glycopyrronium tosylate should be applied to clean dry skin on the underarm areas once daily. Glycopyrronium tosylate should not be used more frequently than once every 24 hours.