Glytone Clarifying Gel

Generic name:hydroquinone
Dosage form: gel
Drug class:Topical depigmenting agents

Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Glytone

HYDROQUINONE USP, 4%

Skin Lightening Gel

Rx Only

FOR EXTERNAL USE ONLY

NOT FOR OPHTHALMIC USE

I. DESCRIPTION

Each gram of Glytone Hydroquinone USP, 4% Skin Lightening Gel contains 40 mg of Hydroquinone USP in a gel base of Purified Water, Propylene Glycol, Carbomer 940, Sodium Bisulfite, Edetate Disodium, Sorbic Acid, and Glycerin. The chemical name for hydroquinone is: 1,4-benzenediol. The molecular formula is C6H6O2 and molecular weight is 110.11. Hydroquinone has the following structural formula:

Hydroquinone Structural Formula

II. CLINICAL PHARMACOLOGY

Topical application of hydroquinone produces a reversible depigmentation of the skin by inhibition of the enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine (dopa) and suppression of other melanocyte metabolic processes. Exposure to sunlight or ultraviolet light will cause repigmentation of the treated areas.

III. INDICATIONS AND USAGE

Glytone Skin Lightening Gel is indicated for the gradual lightening of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation.

IV. CONTRAINDICATIONS

Prior history of sensitivity or allergic reaction to this product or any of its ingredients....