Generic name: allopurinol sodium
Dosage form: injection, powder, lyophilized, for solution
Drug classes:Antigout agents, Antihyperuricemic agents
Medically reviewed by Drugs.com. Last updated on Mar 1, 2022.
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Allopurinol Injection Description
Allopurinol for Injectionis a sterile, white, lyophilized powder or cake, in a single-dose vial for reconstitution. Each vial contains 500 mg of allopurinol equivalent to 580.7 mg of allopurinol sodium and 153 mg of sodium hydroxide as a solubilizer. Sodium hydroxide is also used as a pH adjuster. Allopurinol for Injection contains no preservatives.
Allopurinol is a xanthine oxidase inhibitor. The chemical name for allopurinol sodium is 1, 5-dihydro-4H-pyrazolo [3,4-d] pyrimidin-4-one monosodium salt. It is a white amorphous mass with a molecular weight of 158.09 and molecular formula C5H3N4NaO. The structural formula is:
The pKa of allopurinol sodium is 9.31
Allopurinol Injection - Clinical Pharmacology
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