Golimumab
Generic name: golimumab [ goe-LIM-ue-mab ]
Brand names: Simponi, Simponi Aria, Simponi SmartJect
Dosage forms: intravenous solution (50 mg/4 mL); subcutaneous solution (100 mg/mL; 50 mg/0.5 mL)
Drug class:TNF alfa inhibitors
What is golimumab?
Golimumab is used to treat rheumatoid arthritis and ankylosing spondylitis in adults.
Golimumab is also used to treat psoriatic arthritis and polyarticular juvenile idiopathic arthritis in adults and children at least 2 years old.
Golimumab is also used to treat ulcerative colitis (UC) in adults when other medicines have not worked or could not be tolerated.
Golimumab is sometimes given with methotrexate or a steroid medicine.
Golimumab may also be used for purposes not listed in this medication guide.
Warnings
You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, aches, tiredness, cough, skin sores, diarrhea, or burning when you urinate.
If you have ever had tuberculosis or hepatitis B, golimumab can cause these conditions to come back or get worse. You should be tested for these conditions before you start using golimumab.
Before taking this medicine
You should not use golimumab if you are allergic to it.
Tell your doctor if you have ever had:
active or chronic infections;
a nerve-muscle disease such as multiple sclerosis or Guillain-Barré syndrome;
cancer or lymphoma;
congestive heart failure;
psoriasis; or
if you are scheduled to receive any vaccine.
Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.
Using golimumab may increase your risk of developing autoimmune disorders or cancer, including skin cancer. Talk to your doctor about this risk and what symptoms to watch for.
Golimumab may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young me...
