Goserelin Implant
Generic name: goserelin (implant) [ GOE-se-REL-in ]
Brand name: Zoladex
Dosage form: subcutaneous implant (10.8 mg; 3.6 mg)
Drug classes:Gonadotropin releasing hormones, Hormones / antineoplastics
What is goserelin?
Goserelin is a man-made form of a hormone that regulates many processes in the body. It overstimulates the body's own production of certain hormones, which causes that production to shut down temporarily.
Goserelin implants are used to treat symptoms of prostate cancer in men.
The goserelin implant is also used in women to treat breast cancer or endometriosis. These implants are also used in women to prepare the lining of the uterus for endometrial ablation (a surgery to correct abnormal uterine bleeding).
Goserelin is sometimes used in combination with another cancer drug called flutamide.
Warnings
Unless you are being treated for advanced breast cancer, you should not use a goserelin implant during pregnancy.
Goserelin can harm an unborn baby or cause birth defects. Unless you are being treated for advanced breast cancer, you should not use goserelin during pregnancy. Use effective non-hormonal (barrier) birth control during treatment and for at least 12 weeks after treatment ends. Tell your doctor right away if you become pregnant during treatment. You should not breast-feed while you are using this medicine.
You should not use this medicine if you are allergic to goserelin or to similar hormone medications such as leuprolide (Lupron, Eligard, Viadur), nafarelin (Synarel), or ganirelix (Antagon).
Before you receive goserelin, tell your doctor if you have osteoporosis, diabetes, urination problems, a condition affecting your spine, a history of heart attack or stroke, risk factors for coronary artery disease (such as high blood pressure, high cholesterol, smoking, or being overweight), or if you have abnormal bleeding that your doctor has not checked.
Goserelin can decrease bone mineral density, which may increase your risk of developing osteoporosis. This risk may be greater if you smoke, drink alcohol frequently, have a family history of osteoporosis, or use certain drugs such as seizure medications or steroids. Talk to your doctor about your individual risk of bone loss.
Call your doctor at once if you have a serious side effect while using goserelin, such as severe numbness or tingling in your legs or feet, muscle weakness, problems with balance or coordination, loss of bladder or bowel control, urinating less than usual, pain or burning when you urinate, blood in your urine or stools, easy bruising, increased thirst or urination, fruity breath odor, trouble breathing, sudden numbne...
