HepatAmine

Generic name:isoleucine, leucine, lysine acetate, methionine, phenylalanine, threonine, tryptophan, valine, alani
Dosage form: injection, solution
Drug class:Intravenous nutritional products

Medically reviewed by Drugs.com. Last updated on Sep 1, 2020.

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HepatAmine Description

HepatAmine® (8% Amino Acid Injection) is a sterile, nonpyrogenic, hypertonic solution containing crystalline amino acids. A 500 mL unit provides a total of 40 g of amino acids and 6 g of nitrogen (38 g of protein equivalent).

Each 100 mL contains:

Essential Amino Acids

Isoleucine USP.....0.90 g

Leucine USP.....1.10 g

Lysine.....0.61 g

(added as Lysine Acetate USP.....0.86 g)

Methionine USP.....0.10 g

Phenylalanine USP.....0.10 g

Threonine USP.....0.45 g

Tryptophan USP.....0.066 g

Valine USP.....0.84 g

Nonessential Amino Acids

Alanine USP.....0.77 g

Arginine USP.....0.60 g

Histidine USP.....0.24 g

Proline USP.....0.80 g

Serine USP.....0.50 g

Glycine USP.....0.90 g

Cysteine.....<0.014 g

(as Cysteine HCl•H2O USP.....<0.020 g)

Phosphoric Acid NF.....0.115 g

Sodium Bisulfite (as an antioxidant).....<0.1 g

Water for Injection USP.....qs

pH adjusted with Glacial Acetic Acid USP

pH: 6.5 (6.0–6.8)

Calculated Osmolarity: 785 mOsmol/liter

Concentration of Electrolytes (mEq/liter): Sodium 10; Chloride <3

Phosphate (HPO) 20 (10 mmole P/liter); Acetate Approx. 62 (provided as acetic acid and Iysine acetate)

HepatAmine - Clinical Pharmacology

HepatAmine® provides a mixture of essential and nonessential amino acids with high concentrations of the branched chain amino acids isoleucine, leucine, and valine, and low concentrations of methionine and the aromatic amino acids phenylalanine and tryptophan, relative to general purpose amino acid injections. This amino acid composition has ...