Alpelisib
Generic name: alpelisib [ al-PEL-i-sib ]
Brand names: Piqray, Vijoice
Dosage form: oral tablet (150 mg; 200 mg; 200 mg-50 mg)
Drug class:PI3K inhibitors
What is alpelisib?
Alpelisib is used in men and postmenopausal women with HR-positive, HER2-negative breast cancer that is advanced or has spread to other parts of the body (metastatic).
Alpelisib is used only if your cancer has a specific genetic marker (an abnormal "PIK3CA" gene). Your doctor will test you for this gene.
Alpelisib is given in combination with fulvestrant (Faslodex).
Alpelisib may also be used for purposes not listed in this medication guide.
Warnings
Call your doctor right away if you have severe diarrhea.
Before taking this medicine
You should not use alpelisib if you are allergic to it.
Tell your doctor if you have ever had:
diabetes; or
a severe skin rash (skin pain, redness, peeling, burning eyes, blistering of your lips or mouth).
Although, alpelisib is for use only in women who can no longer get pregnant, you may need to have a negative pregnancy test before starting this treatment. Tell your doctor if you think you may be pregnant.
Alpelisib and fulvestrant both can harm an unborn baby or cause birth defects if the mother or the father is using these medicines.
If you are a woman, do not use alpelisib if you are pregnant. Use effective birth control to prevent pregnancy while you are using alpelisib and for at least 1 week after your last dose.
If you are a man, use condoms and effective birth control if your sex partner is pregnant or is able to get pregnant. Keep using birth control for at least 1 week after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using alpelisib.
Women who also take fulvestrant may need to prevent pregnancy for at least 1 year after treatment ends. Ask your doctor about all how long to keep using birth control.
Alpelisib and fulvestrant may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because these medicines can harm an unborn baby.
Do not breastfeed while using alpelisib, and for at least 1 week after your last dose. You may not be able to breastfeed for 1 year after your last dose of fulvestrant. Ask your doctor.
How should I take alpelisib?
Follow all directions on your prescription label and read all medication gui...
