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Hepatitis B immune globulin
  • Treatments
  • Exposure to Hepatitis B Virus

Hepatitis B immune globulin

Generic name: hepatitis B immune globulin [ HEP-a-TYE-tis-B-im-MYOON-GLOB-yoo-lin ]
Brand names: HepaGam B, HepaGam B NovaPlus, Hyperhep B, Nabi-HB, H-BIG, ... show all 8 brands
Dosage forms: injectable solution (-); intramuscular solution (-)
Drug class:Immune globulins

Medically reviewed by Drugs.com on Aug 3, 2021. Written by Cerner Multum.

What is hepatitis B immune globulin?

Hepatitis B immune globulin is made from human plasma containing proteins that protect against the type B form of hepatitis (inflammation of the liver).

Hepatitis B immune globulin is used to prevent hepatitis B in people receiving a liver transplant, and in babies born to mothers infected with hepatitis B. It is also used to prevent hepatitis B in people who have been exposed to hepatitis B through contaminated blood products, sexual contact with an infected person, or living in a home with an infected person.

Hepatitis B immune globulin is not a vaccine. Therefore it will not provide long-term protection from hepatitis B. For long-term protection you must receive a hepatitis B vaccine such as Engerix-B, Recombivax HB, or Twinrix.

Hepatitis B immune globulin may also be used for purposes not listed in this medication guide.

Warnings

Hepatitis B immune globulin may increase your risk of blood clots, especially if you have heart disease or a history of blood clots, or if you need to use a blood thinner, if you are an older adult, if you are bedridden, if you take birth control pills or hormone replacement, or if you use certain types of catheters.

Call your doctor at once if you have: sudden numbness or weakness (especially on one side of the body); chest pain, trouble breathing, rapid heart rate, coughing up blood; or if you have pain, swelling, warmth, or redness in your arms or legs.

Before taking this medicine

You should not receive hepatitis B immune globulin if you are allergic to it.

Hepatitis B immune globulin may increase your risk of blood clots, especially if you have: