Hepatitis b immune globulin (Intramuscular)

Medically reviewed by Drugs.com. Last updated on Feb 25, 2022.

Commonly used brand name(s)

In the U.S.

• Bayhep B
• HepaGam B
• HyperHEP B
• Nabi-HB
• Nabi-HB NovaPlus

Available Dosage Forms:

• Solution

Therapeutic Class: Immune Serum

Uses for hepatitis b immune globulin

Hepatitis B immune globulin (Human) injection is used to prevent hepatitis B from occurring again in HBsAg-positive liver transplant patients who have had liver transplants. Hepatitis b immune globulin also helps keep you from getting sick if you have been exposed to hepatitis B virus.

Hepatitis B immune globulin (Human) injection may be used for the following patients:

• Sexual partners of persons with hepatitis B.
• Persons who may be exposed to the virus by means of blood, blood products, or human bites, such as health care workers, employees in medical facilities, patients and staff of live-in facilities and day-care programs for the developmentally disabled, morticians and embalmers, police and fire department personnel, and military personnel.
• Those who have household exposure to persons with acute hepatitis B and babies less than 12 months old whose caregiver tests positive for hepatitis B.
• Babies born to mothers who test positive for hepatitis B.

Hepatitis b immune globulin is to be administered only by or under the supervision of your doctor.

Before using hepatitis b immune globulin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For hepatitis b immune globulin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to hepatitis b immune globulin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of hepatitis B immune globulin injection in the pediatric population. However, safety and efficacy have been established in children who are receiving similar medicines for prevention of hepatitis B infection after exposure to hepatitis B virus.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hepatitis B immune globulin injection in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving hepatitis B immune globulin injection.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Wh...