Alpha 1-proteinase inhibitor
Generic name: alpha 1-proteinase inhibitor [ AL-fa-1-PRO-tee-nase-in-HIB-i-tor ]
Brand names: Aralast NP, Glassia, Prolastin-C, Zemaira, Prolastin, Aralast
Dosage forms: intravenous powder for injection (human); intravenous solution (human)
Drug class:Miscellaneous respiratory agents
What is alpha 1-proteinase inhibitor?
Alpha 1-proteinase inhibitor is a protein (alpha 1-antitrypsin) that occurs naturally in the body and helps prevent breakdown of tissues in the lungs. People who lack this protein because of a genetic deficiency can develop damage to the air sacs in the lungs (emphysema).
Alpha 1-proteinase inhibitor is used to treat alpha 1-antitrypsin deficiency in people with symptoms of emphysema.
Alpha 1-proteinase inhibitor will not cure alpha 1-antitrypsin deficiency, and may not slow the progression of emphysema.
Alpha 1-proteinase inhibitor may also be used for purposes not listed in this medication guide.
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Before taking this medicine
You should not use alpha 1-proteinase inhibitor if:
you've had a severe allergic reaction to an alpha 1-proteinase inhibitor; or
you have an IgA (immunoglobulin A) deficiency or antibody against IgA.
Tell your doctor if you have ever had:
liver disease; or
chronic obstructive pulmonary disease (COPD), or other breathing disorder.
Tell your doctor if you are pregnant or breastfeeding.
Not approved for use by anyone younger than 18 years old.
Alpha 1-proteinase inhibitor is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.
How should I use alpha 1-proteinase inhibitor?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Alpha 1-proteinase inhibitor is injected into a vein, usually once per week.
Your first dose may be given in a medical setting where any serious side effects can be quickly treated.
Ask your doctor or pharmacist if you don't understand how to use an injection.
Be sure you understand how to properly mix the powder form of alpha 1-proteinase inhibitor with a liquid (diluent)...
