Hetastarch/sodium chloride (Intravenous)
Medically reviewed by Drugs.com. Last updated on Feb 11, 2022.
Warning: Mortality; Kidney Injury; CoagulopathyUse of hydroxyethylstarch (HES) products, including hetastarch/sodium chloride, increases risk of mortality, kidney injury, and coagulopathy. Do not use hydroxyethylstarch (HES) products, including hetastarch/sodium chloride, unless adequate alternative treatment is unavailable .
Commonly used brand name(s)
In the U.S.
- Hespan
Available Dosage Forms:
- Solution
Therapeutic Class: Volume Expander
Chemical Class: Hydroxyethyl Starch
Uses for hetastarch/sodium chloride
Hespan® injection is used to treat low blood volume (hypovolemia) when other treatment is not available. It is also used in a procedure called leukapheresis.
Hetastarch/sodium chloride is to be given only by or under the supervision of your doctor.
Before using hetastarch/sodium chloride
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For hetastarch/sodium chloride, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to hetastarch/sodium chloride or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies on the relationship of age to the effects of Hespan® injection have not been performed in the pediatric population. Safety and efficacy have not been established.
Geriatric
No information is available on the relationship of age to the effects of Hespan® injection in geriatric patients.
Breastfeeding
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of hetastarch/sodium chloride. Make sure you tell your doctor if you have any other medical problems, especially:
- Allergy to corn starch or
- Heart or blood vessel disease or
- Kidney disease or
- Liver disease—Use with caution. May make these conditions worse.
- Heart bypass—Use in not recommended in patients undergoing this surgery.
- Infection (eg, sepsis), severe or
- Surgery or