Hyaluronidase, pertuzumab, and trastuzumab
Generic name: hyaluronidase, pertuzumab, and trastuzumab [ HYE-al-ure-ON-i-dase, per-TOOZ-ue-mab, and-tras-TOOZ-ue-mab ]
Brand name: Phesgo
Dosage form: subcutaneous solution (20,000 units-600 mg-600 mg/10 mL; 30,000 units-1200 mg-600 mg/15 mL)
Drug class:HER2 inhibitors
What is hyaluronidase, pertuzumab, and trastuzumab?
Hyaluronidase, pertuzumab, and trastuzumab is a combination cancer medicine that is used alone or with other medicines to treat early-stage breast cancer.
hyaluronidase, pertuzumab, and trastuzumab is also used to treat HER2-positive breast cancer that is advanced or has spread to other parts of the body (metastatic).
Hyaluronidase, pertuzumab, and trastuzumab is used for breast cancer only if your tumor tests positive for a protein called human epidermal growth factor receptor 2 (HER2). HER2 protein can speed the growth of cancer cells.
Hyaluronidase, pertuzumab, and trastuzumab may also be used for purposes not listed in this medication guide.
Warnings
This medicine can cause life-threatening heart or lung problems. Call your doctor at once if you have trouble breathing, swelling or rapid weight gain, fast or pounding heartbeats, or if you feel light-headed.
Do not use if you are pregnant. Use effective birth control during treatment and for at least 7 months after your last dose.
Before taking this medicine
You should not be treated with hyaluronidase, pertuzumab, and trastuzumab if you are allergic to hyaluronidase, pertuzumab, or trastuzumab.
Tell your doctor if you have ever had:
congestive heart failure;
a heart attack or heart rhythm disorder;
uncontrolled high blood pressure;
a weak immune system caused by chemotherapy; or
chemotherapy treatment with doxorubicin.
You may need to have a negative pregnancy test before starting this treatment.
Do not use hyaluronidase, pertuzumab, and trastuzumab if you are pregnant. It could cause birth defects or death to the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 7 months after your last dose. Tell your doctor right away if you think you might be pregnant.
If you are pregnant or you become pregnant within 7 months after being treated with this medicine:...
