Hydase

Generic name:hyaluronidase (injection route, subcutaneous route) [ hye-al-ure-ON-i-dase ]
Drug class:Miscellaneous uncategorized agents

Medically reviewed by Drugs.com. Last updated on Jun 4, 2022.

Commonly used brand name(s)

In the U.S.

• Amphadase
• Hydase
• Hylenex
• Vitrase

Available Dosage Forms:

• Solution

Therapeutic Class: Tissue Permeability Modifier

Pharmacologic Class: Enzyme

Uses for Hydase

Hyaluronidase is a natural substance found in the body, which is collected from either cows or pigs. It is cleaned up to remove animal substances. It may also be produced in a laboratory that recreates it from human albumin sources.

Hyaluronidase injection is a spreading substance. It is used with other medicines given under the skin to improve their uptake by the body. This method of drug delivery is only used when the drug cannot be given by injection into a vein. Hyaluronidase injection is also used to increase absorption of fluids or medicines that are injected into your skin. It also used to help improve absorption of radioactive substances during a procedure called subcutaneous urography.

This medicine is to be given only by or under the direct supervision of a doctor.

Before using Hydase

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of hyaluronidase injection in children.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hyaluronidase injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are p...