Hydase Injection
Generic name:hyaluronidase
Dosage form: injection, solution
Drug class:Miscellaneous uncategorized agents
Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- How Supplied/Storage and Handling
- Patient Counseling Information
Indications and Usage for Hydase Injection
Absorption and Dispersion of Injected Drugs
Hydase™ (hyaluronidase injection) is indicated as an adjuvant to increase the absorption and dispersion of other injected drugs.
Hypodermoclysis
Hydase™ is indicated as an adjuvant in subcutaneous fluid administration for achieving hydration.
Subcutaneous Urography
Hydase™ is indicated as an adjuvant in subcutaneous urography for improving resorption of radiopaque.
Hydase Injection Dosage and Administration
Important Administration Instructions
Do not administer Hydase intravenously because hyaluronidase is enzyme is rapidly inactivated with intravenous administration.
Hydase™ may be administered for infiltration use, interstitial use, intramuscular use, intraocular use, retrobulbar use, soft tissue use and subcutaneous use.
Visually inspect parenteral drug products for particulate matter and discoloration prior to administration, whenever the solution and container permit.
Always use aseptic precautions.
Absorption and Dispersion of Subcutaneously Injected Drugs
Absorption and dispersion of other injected drugs may be enhanced by adding 50 to 300 Units, most typically 150 Units of hyaluronidase, to the injection solution.
It is recommended that appropriate references be consulted regarding physical or chemical incompatibilities before adding Hydase™ to a solution containing another drug.
Hypodermoclysis
Insert needle with aseptic precautions. With tip lying free and movable between skin and muscle, begin clysis; fluid should start in readily without pain or lump. Then inject Hydase™ (h...
