Hydralazine and isosorbide dinitrate
Generic name: hydralazine and isosorbide dinitrate [ hye-DRAL-a-zeen-and-EYE-soe-SOR-bide-dye-NYE-trate ]
Brand name: BiDil
Dosage form: oral tablet (37.5 mg-20 mg)
Drug class:Miscellaneous antihypertensive combinations
What is hydralazine and isosorbide dinitrate?
Hydralazine is a vasodilator. It relaxes (widens) veins and arteries, which makes it easier for your heart to pump.
Isosorbide dinitrate is in a group of drugs called nitrates. Isosorbide dinitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.
Hydralazine and isosorbide dinitrate is a combination medicine used to treat heart failure.
Hydralazine and isosorbide dinitrate may also be used for purposes not listed in this medication guide.
Warnings
Do not use hydralazine and isosorbide dinitrate if you are taking medicine to treat erectile dysfunction or pulmonary arterial hypertension (PAH). This includes sildenafil (Viagra, Revatio), avanafil (Stendra), tadalafil (Cialis, Adcirca), vardenafil (Levitra, Staxyn), and riociguat (Adempas). Serious, life-threatening side effects may occur.
Before taking this medicine
Do not use hydralazine and isosorbide dinitrate if you are taking medicine to treat erectile dysfunction or pulmonary arterial hypertension (PAH). This includes sildenafil (Viagra, Revatio), avanafil (Stendra), tadalafil (Cialis, Adcirca), vardenafil (Levitra, Staxyn), and riociguat (Adempas). Serious, life-threatening side effects may occur.
You should not use hydralazine and isosorbide dinitrate if you are allergic to hydralazine, isosorbide dinitrate, isosorbide mononitrate, or nitroglycerin.
To make sure hydralazine and isosorbide dinitrate is safe for you, tell your doctor if you have:
