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Hydrochlorothiazide and irbesartan
  • Treatments
  • High Blood Pressure

Hydrochlorothiazide and irbesartan

Generic name: hydrochlorothiazide and irbesartan [ HYE-droe-KLOR-oh-THYE-a-zide-and-ir-be-SAR-tan ]
Brand name: Avalide
Dosage form: oral tablet (12.5 mg-150 mg; 12.5 mg-300 mg)
Drug class:Angiotensin II inhibitors with thiazides

Medically reviewed by Drugs.com on Feb 15, 2021. Written by Cerner Multum.

What is hydrochlorothiazide and irbesartan?

Hydrochlorothiazide is a diuretic (water pill). Irbesartan is an angiotensin II receptor blocker (sometimes called an ARB blocker).

Hydrochlorothiazide and irbesartan is a combination medicine used to treat high blood pressure (hypertension).

Hydrochlorothiazide and irbesartan may also be used for purposes not listed in this medication guide.

Warnings

You should not use hydrochlorothiazide and irbesartan if you are unable to urinate, or if you are allergic to sulfa drugs.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

If you have diabetes, do not use hydrochlorothiazide and irbesartan together with any medication that contains aliskiren (a blood pressure medicine).

Before taking this medicine

You should not use this medicine if you are allergic to irbesartan or hydrochlorothiazide, or:

  • if you are unable to urinate; or

  • if you are allergic to sulfa drugs.

If you have diabetes, do not use hydrochlorothiazide and irbesartan together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking hydrochlorothiazide and irbesartan with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Irbesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breas...