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Hydrochlorothiazide and losartan
  • Treatments
  • High Blood Pressure

Hydrochlorothiazide and losartan

Generic name: hydrochlorothiazide and losartan [ HYE-droe-KLOR-oh-THYE-a-zide-and-loe-SAR-tan ]
Brand name: Hyzaar
Dosage form: oral tablet (12.5 mg-100 mg; 12.5 mg-50 mg; 25 mg-100 mg)
Drug class:Angiotensin II inhibitors with thiazides

Medically reviewed by Drugs.com on Jan 28, 2021. Written by Cerner Multum.

What is hydrochlorothiazide and losartan?

Hydrochlorothiazide is a diuretic (water pill). Losartan is an angiotensin II receptor antagonist (sometimes called an ARB blocker).

Hydrochlorothiazide and losartan is a combination medicine used to treat high blood pressure (hypertension). It is also used to lower the risk of stroke in certain people with heart disease.

Hydrochlorothiazide and losartan may also be used for purposes not listed in this medication guide.

Warnings

You should not use hydrochlorothiazide and losartan if you are unable to urinate.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

If you have diabetes, do not use hydrochlorothiazide and losartan together with any medication that contains aliskiren (a blood pressure medicine).

Before taking this medicine

You should not use this medicine if you are allergic to hydrochlorothiazide or losartan, if you are unable to urinate.

If you have diabetes, do not use hydrochlorothiazide and losartan together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking hydrochlorothiazide and losartan with aliskiren if you have kidney disease.

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