Hydrochlorothiazide and spironolactone

Generic name: hydrochlorothiazide and spironolactone [ HYE-dro-KLOR-oh-THY-a-zide-and-spir-ON-oh-LAK-tone ]
Brand name: Aldactazide
Dosage form: oral tablet (25 mg-25 mg; 50 mg-50 mg)
Drug class:Potassium sparing diuretics with thiazides

Medically reviewed by Drugs.com on Mar 5, 2021. Written by Cerner Multum.

What is hydrochlorothiazide and spironolactone?

Hydrochlorothiazide is a thiazide diuretic (water pill). Spironolactone is a potassium-sparing diuretic.

Hydrochlorothiazide and spironolactone is a combination medicine used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. hydrochlorothiazide and spironolactone also treats high blood pressure (hypertension), or low potassium levels (hypokalemia) caused by using a diuretic.

Do not use this medicine for any condition that has not been checked by your doctor.

Hydrochlorothiazide and spironolactone may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if you have kidney problems, Addison's disease, high blood levels of calcium or potassium, an allergy to sulfa drugs, or if you are unable to urinate.

Before taking this medicine

You should not use hydrochlorothiazide and spironolactone if you are allergic to hydrochlorothiazide or spironolactone, or if you have:

• kidney disease or urination problems;

• liver disease;

• high levels of calcium or potassium in your blood;

• an allergy to sulfa drugs; or

• Addison's disease (an adrenal gland disorder).

Tell your doctor if you have ever had:

• cirrhosis or other liver disease;

• severe kidney disease;

• asthma or allergies;

• glaucoma;

• gout;

• diabetes; or

• lupus.

In animal studies, spironolactone caused certain types of tumors. It is not known whet...