Dosage form: injection, solution, concentrate
Drug classes:Impotence agents, Vasodilators
Medically reviewed by Drugs.com. Last updated on Jan 24, 2022.
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Apnea is experienced by about 10 to 12% of neonates with congenital heart defects treated with Alprostadil injection. Apnea is most often seen in neonates weighing less than 2 kg at birth and usually appears during the first hour of drug infusion. Therefore, respiratory status should be monitored throughout treatment, and Alprostadil injection should be used where ventilatory assistance is immediately available.
Alprostadil Description
Alprostadil injection USP for intravascular infusion contains 500 micrograms Alprostadil, more commonly known as prostaglandin E1, in 1 mL dehydrated alcohol.
The chemical name for Alprostadil is (1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxy-1-octenyl]-5-oxocyclopentane heptanoic acid, and the molecular weight is 354.49.
Alprostadil is a white to off-white crystalline powder with a melting point between 110° and 116°C. Its solubility at 35°C is 8000 micrograms per 100 mL double distilled water. Alprostadil has a m...
