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Hydrocortisone (EENT)
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  • AHFS Monographs

Hydrocortisone (EENT)

Class: Corticosteroids
ATC Class: S03CA04
VA Class: OP300
Chemical Name: 11ß, 17, 21-trihydroxypregn-4-ene-3,20-dione
CAS Number: 50-23-7


Hydrocortisone, Hydrocortisone Acetate (EENT) is also contained as an ingredient in the following combinations:
Colistin and Neomycin Sulfates and Hydrocortisone Acetate
Hydrocortisone and Acetic Acid
Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone
Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone Acetate
Neomycin and Polymyxin B Sulfates and Hydrocortisone
Polymyxin B Sulfates and Hydrocortisone

Introduction

A corticosteroid secreted by the adrenal cortex.

Uses for Hydrocortisone (EENT)

Ophthalmic Inflammation

Treatment of corticosteroid-responsive ocular inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.

Treatment of chronic anterior uveitis.

Treatment of corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies.

Commercially available only in fixed combination with anti-infectives; use only when such combination therapy is indicated. (See Bacterial Ophthalmic Infections under Uses.)

Bacterial Ophthalmic Infections

Used for anti-inflammatory properties in conjunction with appropriate anti-infective therapy in some bacterial infections of the eye; used in fixed combination with neomycin and polymyxin B sulfates, or with neomycin and polymyxin B sulfates and bacitracin zinc when such combination therapy is indicated. If an ophthalmic corticosteroid is used in combination with an ophthalmic anti-infective, weigh benefits against risks. (See Infections under Cautions.)

Bacterial Otic Infections

Used for anti-inflammatory properties in conjunction with appropriate anti-infective therapy in some cases of bacterial otitis externa; used in fixed combination with acetic acid, ciprofloxacin hydrochloride, colistin sulfate and neomycin sulfate, or neomycin and polymyxin B sulfates when such combination therapy is indicated. If an otic corticosteroid is used in combination with an otic anti-infective, weigh benefits against risks.

Hydrocortisone (EENT) Dosage and Administration

Administration

Apply topically to the eye or ear.

Shake suspension well prior to use.

Ophthalmic Administration

Apply topically to the eye(s) as an ophthalmic ointment or suspension.

Not for injection.

Avoid contamination of the preparation container.

Otic Administration

Apply topically to the ear(s) as an otic solution or suspension.

Not for injection. Do not instill otic preparations into the eye.

Clean and dry ear canal prior to administration.

To avoid dizziness that may result from instilling a cold preparation into the ear, warm the preparation by holding the bottle in the hands for 1–2 minutes prior to administration. (See Advice to Patients.)

Lie with the affected ear upward prior to drug instillation. Remain in this position for 5 minutes following drug administration to ease penetration of drops into the ear canal.

Use sparingly to prevent an accumulation of excess debris in the ear canal.

Dosage

Commercially available only in fixed combination with an