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Hydrocortisone and pramoxine topical/rectal
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Hydrocortisone and pramoxine (topical/rectal)

Generic name: hydrocortisone and pramoxine (topical/rectal) [ HYE-droe-KOR-ti-sone-and-pra-MOX-een ]
Brand names: Analpram-HC, Epifoam, Pramcort, Pramosone, Pramosone E, ... show all 18 brands
Dosage forms: rectal cream (1%-1%; 2.35%-1%; 2.5%-1%); rectal foam (1%-1%); rectal kit (2.5%-1% with cleansing wipes); rectal lotion (2.5%-1%); topical cream (1.85%-1.15%; 1%-1%; 2.5%-1%); topical foam (1%-1%); topical lotion (1%-1%; 2.5%-1%); topical ointment (1%-1%; 2.5%-1%)
Drug class:Anorectal preparations

Medically reviewed by Drugs.com on May 30, 2022. Written by Cerner Multum.

What is hydrocortisone and pramoxine topical?

Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that cause inflammation.

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Hydrocortisone and pramoxine topical (for the skin) is a combination medicine used to treat itching and discomfort caused by allergic reactions, eczema, minor burns, insect bites, or other skin conditions.

Hydrocortisone and pramoxine rectal (for the rectum) is used to treat itching or swelling caused by hemorrhoids or other inflammatory conditions of the rectum or anus.

Hydrocortisone and pramoxine topical may also be used for other purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use hydrocortisone and pramoxine if you are allergic to hydrocortisone or pramoxine, or to any other anesthetics or "numbing medicines."

To make sure hydrocortisone and pramoxine is safe for you, tell your doctor if you have:

  • liver disease;

  • diabetes;

  • problems with your eyes;

  • a stomach or intestinal disorder;

  • a rectal sore or infection; or

  • if you use any drugs that weaken the immune system, including steroids.

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