Hydrocortisone Valerate Cream

Dosage form: cream
Drug class:Topical steroids

Medically reviewed by Drugs.com. Last updated on May 1, 2022.

Hydrocortisone Valerate Cream Description

Hydrocortisone Valerate Cream USP, 0.2% contain hydrocortisone valerate, 11,21-dihydroxy-17-[(1-oxopentyl)oxy]-(11β)-pregn-4-ene-3,20-dione, a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.

Chemically, hydrocortisone valerate is C 26H 38O 6. It has the following structural formula:

Hydrocortisone valerate has a molecular weight of 446.58. It is a white, crystalline solid, soluble in ethanol and methanol, sparingly soluble in propylene glycol and insoluble in water.

Each gram of Hydrocortisone Valerate Cream USP, 0.2% contains 2 mg hydrocortisone valerate in a hydrophilic base composed of carbomer homopolymer type C, dibasic sodium phosphate, methylparaben, sodium lauryl sulfate, polyoxyl 2 stearyl ether, polyoxyethylene (100) stearyl ether, stearyl alcohol, white petrolatum, propylene glycol and purified water.

Hydrocortisone Valerate Cream - Clinical Pharmacology

Like other topical corticos...