Hydrocortisone Valerate Ointment

Dosage form: ointment
Drug class:Topical steroids

Medically reviewed by Drugs.com. Last updated on Jun 1, 2022.

Hydrocortisone Valerate Ointment Description

Hydrocortisone Valerate Ointment USP, 0.2%, contains hydrocortisone valerate, 11,21-dihydroxy-17-[(1-oxopentyl)oxy]-(11β)-pregn-4-ene-3,20-dione, a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.

Chemically, hydrocortisone valerate is C 26H 38O 6. It has the following structural formula:

Hydrocortisone valerate has a molecular weight of 446.58. It is a white, crystalline solid, soluble in ethanol and methanol, sparingly soluble in propylene glycol and insoluble in water.

Each gram of Hydrocortisone Valerate Ointment USP, 0.2% contains 2 mg hydrocortisone valerate in a hydrophilic base composed of carbomer 974P, sodium phosphate dibasic anhydrous, methylparaben, light mineral oil, propylene glycol, purified water, sodium lauryl sulfate, steareth-2, steareth-100, stearyl alcohol, and white petrolatum.

Hydrocortisone Valerate Ointment - Clinical Pharmacology

Like other topical corticosteroids, hydrocortisone valerate has anti-inflammatory, antipruriti...