Hydroquinone Cream with Sunscreens Gel

Generic name: hydroquinone, dioxybenzone and padimate O
Dosage form: gel
Drug class:Topical depigmenting agents

Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Hydroquinone USP, 4%

Skin Bleaching Gel with Sunscreens

FOR EXTERNAL USE ONLY

NOT FOR OPHTHALMIC USE

Rx Only

Hydroquinone Cream with Sunscreens Gel Description

Each gram of Hydroquinone USP, 4% Skin Bleaching Gel with Sunscreens contains 40 mg Hydroquinone USP, 30 mg Dioxybenzone USP, and 50 mg Padimate O USP in a hydroalcoholic base of alcohol (55%), carbomer 940, edetate disodium, propylene glycol, purified water, sodium metabisulfite, and tetrahydroxypropyl ethylenediamine. Chemically, hydroquinone is C6H6O2 and has a molecular weight of 110.11. The chemical name is 1, 4 dihydroxybenzene, and the structural formula of hydroquinone is:

Hydroquinone Cream with Sunscreens Gel - Clinical Pharmacology

Topical application of hydroquinone produces a reversible depigmentation of the skin by inhibition of the enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine (dopa) (Denton, C. et al., 1952)1 and suppression of other melanocyte metabolic processes (Jimbow, K. et al., 1974)2. Exposure to sunlight or ultraviolet light will cause repigmentation of bleached areas (Parrish, J.A. et al., 1978)3.