Generic name: hydroxyzine hydrochloride
Dosage form: injection, solution
Drug classes:Antihistamines, Miscellaneous anxiolytics, sedatives and hypnotics
Medically reviewed by Drugs.com. Last updated on Nov 1, 2021.
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Description
Hydroxyzine hydrochloride has the chemical name of (±)-2-[2-[4-(p-Chloro-a phenylbenzyl) -1-piperazinyl]ethoxy]ethanol dihydrochloride and occurs as a white, odorless powder which is very soluble in water.
It has the following structural formula:
Hydroxyzine Hydrochloride Injection, USP is a sterile aqueous solution intended for intramuscular administration.
Each mL contains: Hydroxyzine HCI 25 mg or 50 mg, Benzyl Alcohol 0.9%, and Water for Injection q.s. pH adjusted with Sodium Hydroxide and/or Hydrochloric Acid.
Clinical Pharmacology
Hydroxyzine hydrochloride is unrelated chemically to phenothiazine, reserpine, and meprobamate. Hydroxyzine has demonstrated its clinical effectiveness in the chemotherapeutic aspect of the total management of neuroses and emotional disturbances manifested by anxiety, tension, agitation, apprehension or confusion.
Hydroxyzine has been shown clinically to be a rapid-acting true ataraxic with a wide margin of safety. It induces a calming effect in anxious, tense, psychoneurotic adults and also in anxious, hyperkinetic child...
