Generic name:palbociclib [ PAL-boe-SYE-klib ]
Drug class:CDK 4/6 inhibitors
What is Ibrance?
Ibrance is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Ibrance is used in men and women to treat HR-positive, HER2-negative breast cancer that has spread to other parts of the body.
In postmenopausal women, Ibrance is given in combination with a hormonal medicine such as letrozole (Femara). In others, Ibrance is given together with fulvestrant (Faslodex).
Warnings
Ibrance affects your lungs or your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, chest pain, shortness of breath, or cough with or without mucus.
Before taking this medicine
You should not use Ibrance if you are allergic to palbociclib. Tell your doctor if you have signs of infection (such as fever or chills).
To make sure Ibrance is safe for you, tell your doctor if you have ever had:
liver disease; or
kidney disease.
Palbociclib can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.
If you are a woman, do not use palbociclib if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for ...
